ska 31 (Tocris)
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93
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Tocris
ska 31
Ska 31, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 18 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ska+31/SKA+31/pm40617384-126-4-29
Average 93 stars, based on 18 article reviews
Ska 31, supplied by Tocris, used in various techniques. Bioz Stars score: 93/100, based on 18 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ska+31/SKA+31/pm40617384-126-4-29
Average 93 stars, based on 18 article reviews
ska 31 - by Bioz Stars,
2026-09
93/100 stars
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other:Article Title: Development of Alzheimer’s Disease Progressively Alters Sex-Dependent K Ca and Sex-Independent K IR Channel Function in Cerebrovascular Endothelium Article Snippet: Effective concentrations of Article Title: Elucidating novel mechanism of action of spiperone for drug repurposing to prevent and treat murine colitis and sepsis. Article Snippet: Aims: While Ca signaling plays a vital role in maintaining normal endothelial function and vascular activity, aberrant Ca signaling in endothelial dysfunction is Jo ur na l P re -p ro of Journal Pre-proof involved in the pathogenesis of inflammation.. As a safe anti-psychotic drug to mobilize Ca signaling, we repurposed spiperone as a potential drug for two intestinal epithelial injury related diseases, colitis and sepsis.. Materials and Methods: Spiperone-induced vasorelaxation of human submucosal arterioles and mesenteric arterioles from wide-type and TRPV4 KO mice was determined by Mulvany-style wire myograph. Article Title: KCa3.1-dependent uptake of the cytotoxic DNA-binding dye Hoechst 33258 into cancerous but not healthy cervical cells Article Snippet: A-967079, 1,2-bis(2-aminophenoxy)ethane-N,N,N0,N0tetraacetic acid tetrakis(acetoxymethyl ester), DCEBIO, SKA 31, TRAM 34, triphenylphosphine oxide, and Article Title: Zinc-sensing receptor activation induces endothelium-dependent hyperpolarization-mediated vasorelaxation of arterioles. Article Snippet: Background: The micronutrient zinc (Zn2+) is critical for cell function as intracellular signaling and endogenous ligand for Zn2+ sensing receptor (ZnR).. Although cytosolic Zn2+ (cyt) signaling in the vascular system was studied previously, role of the ZnR has not been explored in vascular physiology.. Methods: ZnR-mediated relaxation response of human submucosal arterioles and the mesenteric arterioles from wide-type (WT), ZnR-/and TRPV4-/mice were determined by a Mulvany-style wire myograph. Article Title: K Ca 3.1-dependent uptake of the cytotoxic DNA-binding dye Hoechst 33258 into cancerous but not healthy cervical cells Article Snippet: A-967079, 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetraacetic acid tetrakis(acetoxymethyl ester), DCEBIO, SKA 31, TRAM 34, triphenylphosphine oxide, and Article Title: Novel mechanisms of metformin-induced vasorelaxation of mesenteric arterioles via endothelium-dependent hyperpolarization to treat murine colitis. Article Snippet: Research purpose: Metformin, an FDA-approved medication for type 2 diabetes mellitus (T2DM), has been previously reported to have anti-colitis effects via anti-inflammatory, antioxidant, and gut microbiota modulation.. However, the precise mechanisms of metformin-induced vasorelaxation in intestinal resistance vessels in health and ulcerative colitis (UC), remain largely unknown.. Materials and methods: Mulvany-style wire myograph was used to determine metformin-induced vasorelaxation of human submucosal arterioles and mesenteric arterioles from wild-type C57BL/6 mice and transient receptor potential vanilloid 4 knockout mice (TRPV4 KO mice). |